Bệnh Sởi – Nguyên Nhân, Triệu Chứng Và Biện Pháp Phòng Ngừa

Table of Contents

1. Overview

Measles is an acute viral infectious disease that can affect individuals of all ages, particularly children and immunocompromised individuals. Measles is highly contagious via the respiratory route and can cause severe complications. According to the World Health Organization (WHO), there were 160.000 measles-related deaths globally in 2022, predominantly among children under 5 years of age who were unvaccinated or incompletely vaccinated. The majority (over 95%) of fatalities occurred in low-income countries with inadequate healthcare infrastructure.

MEASLES: ETIOLOGY, CLINICAL MANIFESTATIONS, AND PREVENTIVE PROTOCOLS - SANTE Hospital Binh Thanh, HCMC

 2. Causes 

The causative agent of measles is Morbillivirus belonging to the Paramyxoviridae family; the virus is readily transmitted via respiratory droplets from the nose and mouth when an infected person breathes, coughs, sneezes, or talks. The virus can persist in the air and on surfaces for several hours even after the patient has departed, facilitating transmission upon exposure.
  • Sharing food or beverages with a measles patient.
  • Kissing a measles patient.
  • Shaking hands, holding hands, or engaging in close physical contact with a measles patient.
  • Touching a virus-contaminated surface and subsequently touching your mouth, nose, or eyes.
  • Transmission from a pregnant individual to their infant — during pregnancy, childbirth, or breastfeeding.

3. Symptoms

Following measles infection, the incubation period typically ranges from 7 to 14 days. Common initial symptoms include:

  • High fever, exceeding 39°C.
  • Dry cough, runny nose, and sore throat.
  • Red eyes and sensitivity to light (photophobia).
  • Appearance of tiny white spots (known as Koplik spots) inside the oral cavity, typically on the inner lining of the cheeks.

– After a few days, red rashes begin to appear, gradually spreading from the face to the entire body. The rash will last for 5 to 6 days and gradually fade

4. Complications

Measles can lead to numerous severe complications if not treated promptly:
  • Pneumonia: The most common and hazardous complication, especially in young children and older adults.
  • Encephalitis: The incidence of measles-induced encephalitis is approximately 1 in 1,000 cases, which may result in permanent neurological damage.
  • Otitis media: Causes earache, impaired hearing, and middle ear infection.
  • Severe diarrhea and dehydration, leading to critical electrolyte imbalances.
  • Malnutrition: Patients frequently experience loss of appetite and immune system compromise during the illness.
  • Pregnant women have an elevated risk of delivering low-birth-weight infants or experiencing preterm birth.

5. Prevention

MEASLES: ETIOLOGY, CLINICAL MANIFESTATIONS, AND PREVENTIVE PROTOCOLS - Image 2 - SANTE Hospital Binh Thanh, HCMC

Vaccination is the most effective measure to prevent measles. The measles vaccine is routinely administered as a component of the MMR vaccine (measles, mumps, rubella) or MMRV vaccine (measles, mumps, rubella, varicella), indicated for infants aged 12–15 months with a booster dose between 4 and 6 years of age. Comprehensive preventive measures include:
  • Enhancing personal hygiene, disinfecting the nasopharynx, maintaining body warmth, boosting immune resilience, and washing hands frequently.
  • Isolating the infected individual, with the quarantine period lasting from the time measles is suspected until at least 4 days post-onset of the rash.
  • Wearing a face mask when in contact with the patient. N95 respirators are advised for patients, caregivers, and healthcare personnel.

Currently, there is no specific targeted antiviral therapy for measles; management primarily focuses on symptomatic relief and prevention of complications:

  • Consuming adequate warm fluids to maintain hydration and prevent dehydration.
  • Administering antipyretics such as acetaminophen or ibuprofen.
  • Resting and avoiding bright light exposure to alleviate ocular irritation.

– Severe cases require hospitalization for the treatment of complications.

Measles is a serious and highly contagious infectious disease; the most effective preventive measure is completing the full course of measles vaccinations, including scheduled boosters. To ensure optimal efficacy in preventing and controlling measles outbreaks, close collaboration among healthcare systems, media channels, and the community is essential in promoting public health education, personal hygiene practices, and prompt intervention upon detecting cases. We hope this article has provided valuable insights regarding measles. If you observe any of the aforementioned symptoms, please escort the patient to the nearest medical facility for professional examination and clinical care. Refrain from taking any medications without consulting a qualified physician.
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CLINICAL REVIEWER CCHN: 004128/HCM-CCHN
Le Thi Lan Huong

Le Thi Lan Huong

Pediatric Specialist
MD, Spec. I
Dr. Le Thi Lan Huong is an experienced Pediatrician with more than 16 years of experience at leading pediatric hospitals such as Children's Hospital 2 and Vinmec International Hospital. The doctor understands the psychology of children, specializes in treating respiratory diseases, digestive diseases, infectious diseases and provides comprehensive nutritional advice for children from birth to adolescence.
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